IN-VITRO ANTICOAGULANT EFFECT OF AERIAL PARTS EXTRACTS OF YEMENI FAGONIA SCHWEINFURTHII HADIDI

Background: Blood coagulation is a quick and effective process that results in the creation of clots, which demands to monitor. Many illness disorders include an abnormality blood coagulation. This study examined vitro effects methanol, ethyl acetate, n-hexane extracts from aerial parts Fagonia schweinfurthii Hadidi on healthy human volunteers' 
 Methods: The Secondary metabolites were extracted dried crushed F. using n-hexane, respectively. Additionally, tested at different concentrations (10-100 µg/ml) profile, prothrombin time (PT), activated partial thromboplastin (a PTT) apparently volunteers.
 Results: Methanol, significantly (p˃0.05) prolonged PT PTT volunteers with Ethyl acetate methanol recorded largest prolongation correspondingly. highest was achieved 100µg/ml, least obtained 10µg/ml.
 Conclusion: These findings displayed contain phytochemical constituents anticoagulant characteristics could be used treat clotting disorders.
 Peer Review History: Received: 26 April 2022; Revised: 12 June; Accepted: 30 June, Available online: 15 July 2022
 Academic Editor: Dr. DANIYAN Oluwatoyin Michael, Obafemi Awolowo University, ILE-IFE, Nigeria, [email protected]
 UJPR follows most transparent toughest ‘Advanced OPEN peer review’ system. identity authors and, reviewers will known each other. help eradicate any possible malicious/purposeful interference by person (publishing staff, reviewer, editor, author, etc) during review. As result this unique system, all get their due recognition respect, once names are published papers. We expect that, publishing review reports papers, helpful many for drafting article according specifications. Auhors remove error they improve article(s) previous article(s). main purpose it ‘to quality candidate manuscript’. Our check ‘strength weakness manuscript honestly’. There increase perfection, transparency. Received file: Reviewer's Comments:
 Average marks initial stage: 5.5/10
 publication 7.0/10
 Reviewers:
 Gehan Fawzy Abdel Raoof Kandeel, Pharmacognosy Department, National Research Centre, Dokki, 12622, Giza, Egypt, [email protected] Marwa A. Fayed, University Sadat City, [email protected]
 Prof. Hüsniye Kayalar, Ege Turkey, [email protected]
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